Assay Detail
Binding
CHEMBL617192
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Tested in vitro for the inhibition of [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor, expressed in cloned CHO cells.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
(Dipropylamino)-tetrahydronaphthofurans: centrally acting serotonin agonists and dopamine agonists-antagonists
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.60 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL433002 | — | — | 1 | 7.16 |
| CHEMBL328107 | — | — | 1 | 6.84 |
| CHEMBL430332 | — | — | 1 | 5.79 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL433002 | — | Ki | = | 70.0 | nM | 7.16 |
| CHEMBL328107 | — | Ki | = | 146.0 | nM | 6.84 |
| CHEMBL430332 | — | Ki | = | 1637.0 | nM | 5.79 |