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Assay Detail

CHEMBL617209

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
The compound was tested in vitro for its binding affinity towards 5-hydroxytryptamine 2 receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Serotonin 2 (5-HT2) receptor (CHEMBL2096671)
Type PROTEIN FAMILY
Organism Mus musculus

Publication

Novel piperidine sigma receptor ligands as potential antipsychotic drugs.
Gilligan PJ, Cain GA, Christos TE, Cook L, Drummond S, Johnson AL, Kergaye AA, McElroy JF, Rohrbach KW, Schmidt WK.
J Med Chem (1992) 35 : 4344 -4361
PubMed 1360026 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.28 7.28

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL137321 1 7.28

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL137321 Ki = 53.0 nM 7.28