Assay Detail
Binding
CHEMBL617367
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Tested for the binding affinity against the site labelled by the 5-hydroxytryptamine 2A receptor - 5-hydroxytryptamine 2C receptor agonist [125I]- - (+/-)DOI
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Target
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (CHEMBL2111383) ↗| Type | SELECTIVITY GROUP |
| Organism | Rattus norvegicus |
Publication
1-(2,5-Dimethoxy-4-(trifluoromethyl)phenyl)-2-aminopropane: a potent serotonin 5-HT2A/2C agonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.83 | 8.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL136354 | — | — | 1 | 8.96 |
| CHEMBL6620 | — | — | 1 | 8.82 |
| CHEMBL338297 | — | — | 1 | 8.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL136354 | — | Ki | = | 1.1 | nM | 8.96 |
| CHEMBL6620 | — | Ki | = | 1.5 | nM | 8.82 |
| CHEMBL338297 | — | Ki | = | 1.9 | nM | 8.72 |