Assay Detail
Functional
CHEMBL617374
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]5-HT radioligand
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Dihydrobenzofuran analogues of hallucinogens. 4. Mescaline derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.29 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL316527 | — | — | 1 | 6.52 |
| CHEMBL102347 | — | — | 1 | 6.28 |
| CHEMBL319415 | — | — | 1 | 6.26 |
| CHEMBL26687 | MESCALINE | 1.0 | 1 | 6.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL316527 | — | Ki | = | 301.5 | nM | 6.52 |
| CHEMBL102347 | — | Ki | = | 523.0 | nM | 6.28 |
| CHEMBL319415 | — | Ki | = | 555.1 | nM | 6.26 |
| CHEMBL26687 | MESCALINE | Ki | = | 795.1 | nM | 6.10 |