Assay Detail
Binding
CHEMBL617381
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding ability of compound at cloned human 5-hydroxytryptamine 2B receptor using [3H]5-HT 2B as radioligand
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Substituted naphthofurans as hallucinogenic phenethylamine-ergoline hybrid molecules with unexpected muscarinic antagonist activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.78 | 8.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL305275 | — | — | 1 | 8.80 |
| CHEMBL445106 | — | — | 1 | 6.58 |
| CHEMBL307770 | — | — | 1 | 4.95 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL305275 | — | Ki | = | 1.6 | nM | 8.80 |
| CHEMBL445106 | — | Ki | = | 263.0 | nM | 6.58 |
| CHEMBL307770 | — | Ki | = | 11200.0 | nM | 4.95 |