Assay Detail
Binding
CHEMBL617504
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding activity against cloned human 5-hydroxytryptamine 2B receptor using [3H]5-HT as the radioligand.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
A novel (benzodifuranyl)aminoalkane with extremely potent activity at the 5-HT2A receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.63 | 9.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL149024 | — | — | 1 | 9.72 |
| CHEMBL101008 | — | — | 1 | 8.80 |
| CHEMBL6616 | — | — | 1 | 7.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL149024 | — | Ki | = | 0.19 | nM | 9.72 |
| CHEMBL101008 | — | Ki | = | 1.6 | nM | 8.80 |
| CHEMBL6616 | — | Ki | = | 42.7 | nM | 7.37 |