Assay Detail
Binding
CHEMBL617572
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In Vitro Binding affinity againist 5-hydroxytryptamine 1D receptor by displacing [125I]GTI from pig caudate
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and serotonergic activity of benzofuran and dihydrogenzofuran analogues of 5-carboxamidotryptamine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.19 | 8.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL18840 | — | — | 1 | 8.47 |
| CHEMBL19114 | — | — | 1 | 7.37 |
| CHEMBL18710 | — | — | 1 | 6.82 |
| CHEMBL18928 | — | — | 1 | 6.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL18840 | — | IC50 | = | 3.388 | nM | 8.47 |
| CHEMBL19114 | — | IC50 | = | 42.66 | nM | 7.37 |
| CHEMBL18710 | — | IC50 | = | 151.36 | nM | 6.82 |
| CHEMBL18928 | — | IC50 | = | 776.25 | nM | 6.11 |