Assay Detail
Binding
CHEMBL617596
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for binding affinity against human 5-hydroxytryptamine 1D receptor alpha clones expressed in human embryonic kidney (HEK 293) cells line.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | HEK293 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
5-HT1D receptor agonist properties of novel 2-[5-[[(trifluoromethyl)sulfonyl]oxy]indolyl]ethylamines and their use as synthetic intermediates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.51 | 8.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL143767 | — | — | 1 | 8.08 |
| CHEMBL143510 | — | — | 1 | 7.68 |
| CHEMBL143967 | — | — | 1 | 6.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL143767 | — | IC50 | = | 8.4 | nM | 8.08 |
| CHEMBL143510 | — | IC50 | = | 21.0 | nM | 7.68 |
| CHEMBL143967 | — | IC50 | = | 170.0 | nM | 6.77 |