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Assay Detail

CHEMBL617616

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Affinity against serotonergic receptor in the isolated rat stomach fundus
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Tissue Stomach
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 2B (CHEMBL323)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Photoelectron spectra of psychotropic drugs. 6. Relationships between the physical properties and pharmacological actions of amphetamine analogues.
Domelsmith LN, Eaton TA, Houk KN, Anderson GM, Glennon RA, Shulgin AT, Castagnoli N, Kollman PA.
J Med Chem (1981) 24 : 1414 -1421
PubMed 7310818 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 5.27 5.27

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL405 AMPHETAMINE 4.0 1 5.27

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL405 AMPHETAMINE Kd = 5370.32 nM 5.27