5-hydroxytryptamine receptor 2B · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P30994. Use UniProt P30994 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P30994 as the stable identity anchor, then attach disease evidence before program review.
5-hydroxytryptamine receptor 2B
Review this target as 5-hydroxytryptamine receptor 2B, mapped to UniProt P30994. Sequence length is 479 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 5-hydroxytryptamine receptor 2B as ChEMBL target CHEMBL323, mapped to UniProt P30994. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | 5-hydroxytryptamine receptor 2B |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P30994 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 5-hydroxytryptamine receptor 2B |
| UniProt Accession | P30994 |
| Component Type | Protein |
| Sequence Length | 479 aa |
5-hydroxytryptamine receptor 2B
Review this target as 5-hydroxytryptamine receptor 2B, mapped to UniProt P30994. Sequence length is 479 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5270056 | 10.1 | Ki | 0.08 | Preclinical |
| CHEMBL5277645 | 10.0 | Ki | 0.1 | Preclinical |
| CHEMBL5279881 | 10.0 | Ki | 0.1 | Preclinical |
| CHEMBL5280131 | 10.0 | Ki | 0.1 | Preclinical |
| CHEMBL5284094 | 10.0 | Ki | 0.1 | Preclinical |
| CHEMBL94644 | 9.7 | Ki | 0.2 | Preclinical |
| CHEMBL94655 | 9.7 | Ki | 0.2 | Preclinical |
| CHEMBL95121 | 9.7 | Ki | 0.2 | Preclinical |
| CHEMBL96427 | 9.7 | Ki | 0.2 | Preclinical |
| CHEMBL96480 | 9.7 | Ki | 0.2 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 9 | 15 | 6.0 |
| tissue-based format | 8 | 35 | 6.8 |
| cell membrane format | 2 | 12 | 6.8 |
| cell-based format | 1 | 11 | 9.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 10 | 65 | 6.9 |
| assay format | 6 | 19 | 6.3 |
| cell-based format | 1 | 6 | 7.7 |