Compound Detail
CHEMBL5279881
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Basic Information
| ChEMBL ID | CHEMBL5279881 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WDTSATDFWHUGLE-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
350.5
MW (Da)
4.18
ALogP
3
HBA
2
HBD
46.3
PSA (Ų)
0.73
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 10.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2B CHEMBL323 | Ki | 10.0 | 10.0 | 0.1 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2B | Ki | = | 0.1 | nM | 10.0 | Displacement of [3H]-ketanserin from rat 5-HT2B expressed in mouse NIH/3T3 cells... | 33528252 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 33528252 | 10.1021/acs.jmedchem.0c01887 | 5-hydroxytryptamine receptor 2B | 2 |
Data from ChEMBL 36 via Core Engine