Assay Detail
Functional
CHEMBL617627
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Negative log concentration of antagonistic compound was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundus
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Tissue | Stomach |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
New serotonin 5-HT(2A), 5-HT(2B), and 5-HT(2C) receptor antagonists: synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo and heterocycloalkanones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 5.89 | 6.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL358895 | — | — | 1 | 6.19 |
| CHEMBL357517 | — | — | 1 | 6.01 |
| CHEMBL143937 | — | — | 1 | 5.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL358895 | — | Kd | = | 645.65 | nM | 6.19 |
| CHEMBL357517 | — | Kd | = | 977.24 | nM | 6.01 |
| CHEMBL143937 | — | Kd | = | 3467.37 | nM | 5.46 |