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Assay Detail

CHEMBL617850

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to 5-hydroxytryptamine 2C receptor measured using radioligand [3H]Mesulergine in stably transfected NIH3T3 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Cell Type NIH3T3
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 2C (CHEMBL3006)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Influence of chain length and N-alkylation on the selective serotonin receptor ligand 9-(aminomethyl)-9,10-dihydroanthracene.
Runyon SP, Savage JE, Taroua M, Roth BL, Glennon RA, Westkaemper RB.
Bioorg Med Chem Lett (2001) 11 : 655 -658
PubMed 11266163 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.37 7.37

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL47482 1 7.37

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL47482 Ki = 43.0 nM 7.37