Assay Detail
Binding
CHEMBL617866
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for their binding affinity towards 5-hydroxytryptamine 2C receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Novel, potent, and selective 5-HT3 receptor antagonists based on the arylpiperazine skeleton: synthesis, structure, biological activity, and comparative molecular field analysis studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.35 | 8.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL12314 | MESULERGINE | 2.0 | 1 | 8.28 |
| CHEMBL291771 | — | — | 1 | 5.64 |
| CHEMBL417706 | — | — | 1 | 5.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL12314 | MESULERGINE | Ki | = | 5.2 | nM | 8.28 |
| CHEMBL291771 | — | Ki | = | 2300.0 | nM | 5.64 |
| CHEMBL417706 | — | Ki | = | 7200.0 | nM | 5.14 |