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Assay Detail

CHEMBL618081

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity against 5-hydroxytryptamine 5A receptor in HEK 293 cells was determined using [3H]LSD as radioligand
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Cell Type HEK293
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 1A (CHEMBL273)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

N-Arylsulfonylindole derivatives as serotonin 5-HT(6) receptor ligands.
Russell MG, Baker RJ, Barden L, Beer MS, Bristow L, Broughton HB, Knowles M, McAllister G, Patel S, Castro JL.
J Med Chem (2001) 44 : 3881 -3895
PubMed 11689074 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.38 5.38

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL317535 1 5.38

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL317535 Ki = 4200.0 nM 5.38