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Assay Detail

CHEMBL618556

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
The compound was tested for cytotoxic activity against A2780cisR cell line(human ovarian carcinoma
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Cell Type A2780cisR
Confidence 1 — Organism
Curated By Intermediate

Target

A2780cisR (CHEMBL614023)
Type CELL-LINE
Organism Homo sapiens

Publication

N4-(omega-Aminoalkyl)-1-[(omega-aminoalkyl)amino]-4- acridinecarboxamides: novel, potent, cytotoxic, and DNA-binding agents.
Antonini I, Polucci P, Kelland LR, Spinelli S, Pescalli N, Martelli S.
J Med Chem (2000) 43 : 4801 -4805
PubMed 11123989 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.32 6.32

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL342800 1 6.32

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL342800 IC50 = 475.0 nM 6.32