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Assay Detail

CHEMBL619182

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antagonistic activity of corresponding methoxy compound against serotonin 5-HT receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Serotonin (5-HT) receptor (CHEMBL2094123)
Type PROTEIN FAMILY
Organism Rattus norvegicus

Publication

Demethyl analogues of psychoactive methoxyphenalkylamines: synthesis and serotonin receptor affinities.
Glennon RA, Liebowitz SM, Leming-Doot D, Rosecrans JA.
J Med Chem (1980) 23 : 990 -994
PubMed 7411554 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 5.52 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL367501 1 5.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL367501 Kd = 3019.95 nM 5.52