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Assay Detail

CHEMBL620585

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was evaluated for the binding affinity at 5- HT3 receptor subtype
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Serotonin 3 receptor (5HT3) (CHEMBL2111333)
Type PROTEIN FAMILY
Organism Mus musculus

Publication

The serotonin 5-HT4 receptor. 1. Design of a new class of agonists and receptor map of the agonist recognition site.
Buchheit KH, Gamse R, Giger R, Hoyer D, Klein F, Klöppner E, Pfannkuche HJ, Mattes H.
J Med Chem (1995) 38 : 2326 -2330
PubMed 7608898 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.70 6.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL86 METOCLOPRAMIDE 4.0 1 6.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL86 METOCLOPRAMIDE Ki = 200.0 nM 6.70