Assay Detail
ADMET
CHEMBL631604
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In vitro photocytotoxicity is evaluated for photoinduced dose modification
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
In vitro photoinduced cytotoxicity and DNA binding properties of psoralen and coumarin conjugates of netropsin analogues: DNA sequence-directed alkylation and cross-link formation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.92 | 4.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL277932 | — | — | 1 | 4.92 |
| CHEMBL278378 | — | — | 1 | - |
| CHEMBL20465 | — | — | 1 | - |
| CHEMBL280112 | — | — | 1 | - |
| CHEMBL416 | METHOXSALEN | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL277932 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL278378 | — | IC50 | > | 2500.0 | nM | - |
| CHEMBL20465 | — | IC50 | > | 1300.0 | nM | - |
| CHEMBL280112 | — | IC50 | > | 333000.0 | nM | - |
| CHEMBL416 | METHOXSALEN | IC50 | > | 1000.0 | nM | - |