Assay Detail
Binding
CHEMBL636508
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Binding affinity tested against acetylcholinesterase in Torpedo californica
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Torpedo californica |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Interaction of cycloSal-pronucleotides with cholinesterases from different origins. A structure-activity relationship.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.12 | 8.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL107316 | — | — | 1 | 8.48 |
| CHEMBL108726 | — | — | 1 | 7.76 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL107316 | — | Ki | = | 3.3 | nM | 8.48 |
| CHEMBL108726 | — | Ki | = | 17.5 | nM | 7.76 |