Assay Detail
Binding
CHEMBL636716
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Binding affinity towards Acetylcholinesterase from fetal bovine serum
4
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis, chiral chromatographic separation, and biological activities of the enantiomers of 10,10-dimethylhuperzine A.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.91 | 8.23 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL395280 | HUPERZINE A | 2.0 | 1 | 8.23 |
| CHEMBL79874 | — | — | 3 | 8.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL395280 | HUPERZINE A | Ki | = | 5.9 | nM | 8.23 |
| CHEMBL79874 | — | Ki | = | 7.7 | nM | 8.11 |
| CHEMBL79874 | — | Ki | = | 16.7 | nM | 7.78 |
| CHEMBL79874 | — | Ki | = | 30.9 | nM | 7.51 |