Assay Detail
Binding
CHEMBL636896
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Inhibition against Acetylcholinesterase (AChE)
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
A comparative molecular field analysis study of N-benzylpiperidines as acetylcholinesterase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.49 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL127513 | — | — | 1 | 6.82 |
| CHEMBL434811 | — | — | 1 | 6.52 |
| CHEMBL93241 | — | — | 1 | 6.05 |
| CHEMBL339630 | — | — | 1 | 5.27 |
| CHEMBL338596 | — | — | 1 | 4.89 |
| CHEMBL127917 | — | — | 1 | 4.58 |
| CHEMBL127398 | — | — | 1 | 4.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL127513 | — | IC50 | = | 149.97 | nM | 6.82 |
| CHEMBL434811 | — | IC50 | = | 299.92 | nM | 6.52 |
| CHEMBL93241 | — | IC50 | = | 899.5 | nM | 6.05 |
| CHEMBL339630 | — | IC50 | = | 5395.11 | nM | 5.27 |
| CHEMBL338596 | — | IC50 | = | 13001.7 | nM | 4.89 |
| CHEMBL127917 | — | IC50 | = | 26001.6 | nM | 4.58 |
| CHEMBL127398 | — | IC50 | = | 53951.06 | nM | 4.27 |