Assay Detail
Functional
CHEMBL637738
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against acetylcholinesterase in mice at the dose of 4.8 mg/kg via intraperitoneal administration
1
Total Activities
1
Compounds Tested
1
Activity Types
2
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Syntheses and anticholinesterase activity of tetrahydrobenzazepine carbamates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.83 | 6.83 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| DOSE | DOSE | 4.8 | mg.kg-1 | — |
| ROUTE | ROUTE | - | — | Intraperitoneal |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL433041 | EPTASTIGMINE | 2.0 | 1 | 6.83 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL433041 | EPTASTIGMINE | IC50 | = | 148.0 | nM | 6.83 |