Assay Detail
Binding
CHEMBL637744
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Dissociation constant towards Acetylcholinesterase in mouse
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Fragment-based drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 6.86 | 7.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL95 | TACRINE | 4.0 | 1 | 7.75 |
| CHEMBL345124 | PROPIDIUM | — | 1 | 5.96 |
| CHEMBL117651 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL95 | TACRINE | Kd | = | 18.0 | nM | 7.75 |
| CHEMBL345124 | PROPIDIUM | Kd | = | 1100.0 | nM | 5.96 |
| CHEMBL117651 | — | Kd | = | 0.00041 | nM | - |