Assay Detail
ADMET
CHEMBL637825
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pA2 value, a dose-response plot was obtained by determining the response when the concentration of glucagon was varied while the concentration was kept same.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Development of potent truncated glucagon antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 7.58 | 8.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL438045 | — | — | 1 | 8.20 |
| CHEMBL267876 | — | — | 1 | 8.16 |
| CHEMBL413890 | — | — | 1 | 7.25 |
| CHEMBL409896 | — | — | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL438045 | — | Kd | = | 6.31 | nM | 8.20 |
| CHEMBL267876 | — | Kd | = | 6.918 | nM | 8.16 |
| CHEMBL413890 | — | Kd | = | 56.23 | nM | 7.25 |
| CHEMBL409896 | — | Kd | = | 199.53 | nM | 6.70 |