Assay Detail
Functional
CHEMBL638498
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of smooth muscle cell ACAT activity for cells stimulated by native LDL.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cercopithecidae |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Potential antiatherosclerotic agents. 5. An acyl-CoA:cholesterol O-acyltransferase inhibitor with hypocholesterolemic activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.96 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL277986 | CL-277082 | — | 1 | 5.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL277986 | CL-277082 | IC50 | = | 1090.0 | nM | 5.96 |