Assay Detail
Binding
CHEMBL638586
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for inhibitory activity against ACAT from rabbit liver
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryctolagus cuniculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Target
Acyl-CoA:cholesterol acyltransferase (CHEMBL6141) ↗| Type | SINGLE PROTEIN |
| Organism | Oryctolagus cuniculus |
Publication
Polyunsaturated fatty acid anilides as inhibitors of acyl-coA: cholesterol acyltransferase (ACAT).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.26 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL64237 | — | — | 1 | 7.82 |
| CHEMBL304267 | — | — | 1 | 7.25 |
| CHEMBL22373 | CL-976 | — | 1 | 6.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL64237 | — | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL304267 | — | IC50 | = | 56.0 | nM | 7.25 |
| CHEMBL22373 | CL-976 | IC50 | = | 191.0 | nM | 6.72 |