Assay Detail
Binding
CHEMBL639637
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against acyl-CoA:cholesterol acyltransferase (ACAT)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Synthetic conversion of ACAT inhibitor to acetylcholinesterase inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.24 | 7.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL25532 | — | — | 1 | 7.24 |
| CHEMBL283509 | — | — | 1 | - |
| CHEMBL24686 | TERRITREM B | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL25532 | — | IC50 | = | 58.0 | nM | 7.24 |
| CHEMBL283509 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL24686 | TERRITREM B | IC50 | > | 50000.0 | nM | - |