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Assay Detail

CHEMBL640255

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of [3H]-DPCPX binding to adenosine A1 receptor (AR).
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cricetulus griseus
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Adenosine receptor A1 (CHEMBL226)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Fluorosulfonyl-substituted xanthines as selective irreversible antagonists for the A(1)-adenosine receptor.
Beauglehole AR, Baker SP, Scammells PJ.
J Med Chem (2000) 43 : 4973 -4980
PubMed 11150167 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.93 7.93

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL327708 1 7.93

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL327708 IC50 = 11.8 nM 7.93