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Assay Detail

CHEMBL640257

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity against [3H]- CPX binding (post-Xanthine)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cricetulus griseus
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Adenosine receptor A1 (CHEMBL226)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Substituted 1,3-dipropylxanthines as irreversible antagonists of A1 adenosine receptors.
Scammells PJ, Baker SP, Belardinelli L, Olsson RA.
J Med Chem (1994) 37 : 2704 -2712
PubMed 8064798 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 9.03 9.03

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL89939 1 9.03

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL89939 Kd = 0.94 nM 9.03