Assay Detail
Functional
CHEMBL640804
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Tested for Alpha adrenergic receptor antagonistic activity on isolated rat vas deferens
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Tissue | Vas deferens |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Conformational effects on the activity of drugs. 10. Synthesis, conformation, and pharmacological properties of 1-(2,5-dimethoxyphenyl)-2-aminoethanols and their morpholine analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 6 | 4.04 | 4.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1076 | DESGLYMIDODRINE | -1.0 | 1 | 4.04 |
| CHEMBL315827 | — | — | 1 | - |
| CHEMBL88087 | — | — | 1 | - |
| CHEMBL87415 | — | — | 1 | - |
| CHEMBL420791 | — | — | 1 | - |
| CHEMBL86360 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1076 | DESGLYMIDODRINE | Kd | = | 91201.08 | nM | 4.04 |
| CHEMBL315827 | — | Kd | = | 245470.89 | nM | - |
| CHEMBL88087 | — | Kd | = | 1819700.86 | nM | - |
| CHEMBL87415 | — | Kd | = | 331131.12 | nM | - |
| CHEMBL420791 | — | Kd | = | 724435.96 | nM | - |
| CHEMBL86360 | — | Kd | = | 398107.17 | nM | - |