Assay Detail
Binding
CHEMBL641011
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Inhibition constant determined against Acetylcholinesterase (AChE) receptor.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Acetylcholinesterase noncovalent inhibitors based on a polyamine backbone for potential use against Alzheimer's disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.39 | 9.98 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL11805 | CAPROCTAMINE | — | 1 | 9.98 |
| CHEMBL60745 | EDROPHONIUM BROMIDE | — | 1 | 8.79 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL11805 | CAPROCTAMINE | Ki | = | 0.104 | nM | 9.98 |
| CHEMBL60745 | EDROPHONIUM BROMIDE | Ki | = | 1.63 | nM | 8.79 |