Assay Detail
Binding
CHEMBL641013
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity of compound against acetylcholinesterase from human erythrocytes
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 2. Role of the substituents on the phenyl ring and nitrogen atoms of caproctamine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.91 | 7.91 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL173309 | — | — | 1 | 7.91 |
| CHEMBL11805 | CAPROCTAMINE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL173309 | — | Ki | = | 12.2 | nM | 7.91 |
| CHEMBL11805 | CAPROCTAMINE | Ki | = | 104.0 | nM | - |