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Assay Detail

CHEMBL641178

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was evaluated for the inhibition of Hamster Liver mitochondrial ALDH-2
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Cricetulus griseus
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Aldehyde dehydrogenase, mitochondrial (CHEMBL1935)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

The mitochondrial monoamine oxidase-aldehyde dehydrogenase pathway: a potential site of action of daidzin.
Rooke N, Li DJ, Li J, Keung WM.
J Med Chem (2000) 43 : 4169 -4179
PubMed 11063613 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.00 7.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL132065 1 7.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL132065 IC50 = 100.0 nM 7.00