Assay Detail
Binding
CHEMBL641211
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Compound was tested for inhibitory activity against ACAT from Caco-2 microsome in human
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | Caco-2 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Polyunsaturated fatty acid anilides as inhibitors of acyl-coA: cholesterol acyltransferase (ACAT).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.80 | 7.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL304267 | — | — | 1 | 7.37 |
| CHEMBL64237 | — | — | 1 | 6.95 |
| CHEMBL22373 | CL-976 | — | 1 | 6.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL304267 | — | IC50 | = | 43.0 | nM | 7.37 |
| CHEMBL64237 | — | IC50 | = | 113.0 | nM | 6.95 |
| CHEMBL22373 | CL-976 | IC50 | = | 838.0 | nM | 6.08 |