Assay Detail
Functional
CHEMBL641230
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro antitumor activity of compound against AGS cell line (human stomach cancer cells)
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | AGS |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis of OSW-1 analogs with modified side chains and their antitumor activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.39 | 5.86 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL327536 | — | — | 1 | 5.86 |
| CHEMBL262508 | — | — | 1 | 5.85 |
| CHEMBL443535 | — | — | 1 | 5.72 |
| CHEMBL96545 | — | — | 1 | 5.16 |
| CHEMBL92531 | — | — | 1 | 5.14 |
| CHEMBL11359 | CISPLATIN | 4.0 | 1 | 4.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL327536 | — | IC50 | = | 1380.0 | nM | 5.86 |
| CHEMBL262508 | — | IC50 | = | 1420.0 | nM | 5.85 |
| CHEMBL443535 | — | IC50 | = | 1920.0 | nM | 5.72 |
| CHEMBL96545 | — | IC50 | = | 6980.0 | nM | 5.16 |
| CHEMBL92531 | — | IC50 | = | 7260.0 | nM | 5.14 |
| CHEMBL11359 | CISPLATIN | IC50 | = | 24100.0 | nM | 4.62 |