Assay Detail
Binding
CHEMBL641276
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration against Adenylosuccinate synthetase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Adenylosuccinate synthetase isozyme 2 (CHEMBL4875) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Fragment-based drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.33 | 7.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL118357 | — | — | 1 | 7.37 |
| CHEMBL323799 | PHOSPHOHYDANTOCIDIN | — | 1 | 6.17 |
| CHEMBL331373 | HADACIDIN | — | 1 | 5.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL118357 | — | IC50 | = | 43.0 | nM | 7.37 |
| CHEMBL323799 | PHOSPHOHYDANTOCIDIN | IC50 | = | 675.0 | nM | 6.17 |
| CHEMBL331373 | HADACIDIN | IC50 | = | 3500.0 | nM | 5.46 |