Assay Detail
Binding
CHEMBL641280
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity against Adipocyte lipid binding protein
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
Fatty acid-binding protein, adipocyte (CHEMBL2083) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Simple, intuitive calculations of free energy of binding for protein-ligand complexes. 1. Models without explicit constrained water.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 4.79 | 6.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL15594 | ARACHIDONIC ACID | -1.0 | 1 | 6.75 |
| CHEMBL460657 | ELAIDIC ACID | — | 1 | 4.24 |
| CHEMBL46403 | STEARIC ACID | -1.0 | 1 | 4.10 |
| CHEMBL82293 | PALMITIC ACID | -1.0 | 1 | 4.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL15594 | ARACHIDONIC ACID | Kd | = | 180.0 | nM | 6.75 |
| CHEMBL460657 | ELAIDIC ACID | Kd | = | 58000.0 | nM | 4.24 |
| CHEMBL46403 | STEARIC ACID | Kd | = | 80000.0 | nM | 4.10 |
| CHEMBL82293 | PALMITIC ACID | Kd | = | 83000.0 | nM | 4.08 |