Assay Detail
Binding
CHEMBL641394
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Inhibitory concentration against Acetylcholinesterase in rat brain
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Brain |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Fragment-based drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.35 | 9.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL117521 | — | — | 1 | 9.40 |
| CHEMBL323618 | — | — | 1 | 6.41 |
| CHEMBL95 | TACRINE | 4.0 | 1 | 6.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL117521 | — | IC50 | = | 0.4 | nM | 9.40 |
| CHEMBL323618 | — | IC50 | = | 390.0 | nM | 6.41 |
| CHEMBL95 | TACRINE | IC50 | = | 590.0 | nM | 6.23 |