Assay Detail
Binding
CHEMBL641437
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Binding affinity against rat Adenosine A3 receptor from CHO cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Interaction of 1,4-dihydropyridine and pyridine derivatives with adenosine receptors: selectivity for A3 receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 5.12 | 5.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL315984 | — | — | 1 | 5.38 |
| CHEMBL105672 | — | — | 1 | 5.21 |
| CHEMBL1484 | NICARDIPINE | 4.0 | 1 | 4.96 |
| CHEMBL2112411 | — | — | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL315984 | — | Ki | = | 4160.0 | nM | 5.38 |
| CHEMBL105672 | — | Ki | = | 6200.0 | nM | 5.21 |
| CHEMBL1484 | NICARDIPINE | Ki | = | 11000.0 | nM | 4.96 |
| CHEMBL2112411 | — | Ki | = | 12100.0 | nM | 4.92 |