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Assay Detail

CHEMBL641993

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity against A2 adenosine receptor in [3H]adenine-labeled guinea pig cerebral cortical slices
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cavia porcellus
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Adenosine A2 receptor (CHEMBL2094257)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Functionalized congeners of 1,3-dialkylxanthines: preparation of analogues with high affinity for adenosine receptors.
Jacobson KA, Kirk KL, Padgett WL, Daly JW.
J Med Chem (1985) 28 : 1334 -1340
PubMed 2993622 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.75 6.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL283628 1 6.75

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL283628 Ki = 180.0 nM 6.75