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Assay Detail

CHEMBL642228

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Percent displacement of [3H]CGS-21680 from human adenosine A2A receptor expressed in CHO cells at 10 uM
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type CHO
Confidence 9 — Direct single protein target
Curated By Expert

Target

Adenosine receptor A2a (CHEMBL251)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

N6-substituted D-4'-thioadenosine-5'-methyluronamides: potent and selective agonists at the human A3 adenosine receptor.
Jeong LS, Jin DZ, Kim HO, Shin DH, Moon HR, Gunaga P, Chun MW, Kim YC, Melman N, Gao ZG, Jacobson KA.
J Med Chem (2003) 46 : 3775 -3777
PubMed 12930138 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.70 7.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL201706 1 7.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL201706 Ki = 20.0 nM 7.70