Assay Detail
Binding
CHEMBL642297
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Inhibition of [3H]- (R)-P1A binding to adenosine A1 receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Activity of N6-substituted 2-chloroadenosines at A1 and A2 adenosine receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.74 | 8.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL285819 | — | — | 1 | 8.17 |
| CHEMBL420705 | (S)-PIA | — | 1 | 7.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL285819 | — | Ki | = | 6.7 | nM | 8.17 |
| CHEMBL420705 | (S)-PIA | Ki | = | 50.0 | nM | 7.30 |