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Assay Detail

CHEMBL642801

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Inhibition constant was determined from Lineweaver-Burke plot
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

ADMET (CHEMBL612558)
Type ADMET

Publication

A new class of nonsteroidal aromatase inhibitors: design and synthesis of chromone and xanthone derivatives and inhibition of the P450 enzymes aromatase and 17 alpha-hydroxylase/C17,20-lyase.
Recanatini M, Bisi A, Cavalli A, Belluti F, Gobbi S, Rampa A, Valenti P, Palzer M, Palusczak A, Hartmann RW.
J Med Chem (2001) 44 : 672 -680
PubMed 11262078 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.98 8.98

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL159073 1 8.98

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL159073 Ki = 1.05 nM 8.98