Assay Detail
Binding
CHEMBL643125
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Binding affinity at rat adenosine A3 receptor in RBL-2H3 cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Cell Type | RBL-2H3 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Neoceptor concept based on molecular complementarity in GPCRs: a mutant adenosine A(3) receptor with selectively enhanced affinity for amine-modified nucleosides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.08 | 7.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL338352 | — | — | 1 | 7.08 |
| CHEMBL133809 | — | — | 1 | - |
| CHEMBL302376 | — | — | 1 | - |
| CHEMBL133591 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL338352 | — | Ki | = | 84.0 | nM | 7.08 |
| CHEMBL133809 | — | Ki | > | 10.0 | nM | - |
| CHEMBL302376 | — | Ki | > | 10.0 | nM | - |
| CHEMBL133591 | — | Ki | > | 10.0 | nM | - |