Assay Detail
Binding
CHEMBL643145
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity towards rat Adenosine A1 receptor using [3H]-DPCPX
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and use of FSCPX, an irreversible adenosine A1 antagonist, as a 'receptor knock-down' tool.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.29 | 7.94 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL327708 | — | — | 1 | 7.94 |
| CHEMBL68738 | N6-CYCLOPENTYLADENOSINE | — | 1 | 6.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL327708 | — | Ki | = | 11.5 | nM | 7.94 |
| CHEMBL68738 | N6-CYCLOPENTYLADENOSINE | Ki | = | 230.0 | nM | 6.64 |