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Assay Detail

CHEMBL643295

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity against Adenosine A2 receptor from human platelets with [125I]-N6-aminobenzyladenosine
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Adenosine A2 receptor (CHEMBL2094257)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Adenosine A1 antagonists. 3. Structure-activity relationships on amelioration against scopolamine- or N6-((R)-phenylisopropyl)adenosine-induced cognitive disturbance.
Suzuki F, Shimada J, Shiozaki S, Ichikawa S, Ishii A, Nakamura J, Nonaka H, Kobayashi H, Fuse E.
J Med Chem (1993) 36 : 2508 -2518
PubMed 8355252 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.70 5.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL310557 1 5.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL310557 Ki = 2000.0 nM 5.70