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Assay Detail

CHEMBL643366

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Potency against human platelet A2 adenosine receptor by adenylate cyclase activation
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Adenosine A2 receptor (CHEMBL2094257)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

N6-substituted N-alkyladenosine-5'-uronamides: bifunctional ligands having recognition groups for A1 and A2 adenosine receptors.
Olsson RA, Kusachi S, Thompson RD, Ukena D, Padgett W, Daly JW.
J Med Chem (1986) 29 : 1683 -1689
PubMed 3018244 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 5.99 6.17

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL603571 1 6.17
CHEMBL604834 1 5.81

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL603571 EC50 = 680.0 nM 6.17
CHEMBL604834 EC50 = 1550.0 nM 5.81