Assay Detail
Binding
CHEMBL643634
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Inhibition of binding of [3H]prazosin to Alpha-1 adrenergic receptor in rat cortical membranes
5
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Subcellular | Membrane |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Cis- and trans-N-benzyl-octahydrobenzo[g]quinolines. Adrenergic and dopaminergic activity studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.66 | 5.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL133432 | — | — | 1 | 5.66 |
| CHEMBL170475 | — | — | 2 | - |
| CHEMBL170974 | — | — | 2 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL133432 | — | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL170475 | — | IC50 | = | 667000.0 | nM | - |
| CHEMBL170974 | — | IC50 | = | 218000.0 | nM | - |
| CHEMBL170974 | — | IC50 | = | 739000.0 | nM | - |
| CHEMBL170475 | — | IC50 | = | 588000.0 | nM | - |