Assay Detail
Binding
CHEMBL643847
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Inhibitory activity towards Alpha-mannosidase from Almond
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Prunus dulcis |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Derivatives of (2R,3R,4S)-2-aminomethylpyrrolidine-3,4-diol are selective alpha-mannosidase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 4.08 | 4.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL84104 | — | — | 1 | 4.15 |
| CHEMBL84941 | — | — | 1 | 4.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL84104 | — | Ki | = | 71000.0 | nM | 4.15 |
| CHEMBL84941 | — | Ki | = | 98000.0 | nM | 4.01 |